Follicular lymphoma stage 1 treatment?

Follicular Lymphoma - stage I is compleately curable and you have to take all treatments and have consultations with your Oncologist periodically to ensure it does not reoccur. Wish you all the best. Now read about the disease further -





Follicular lymphoma (FL) is the most common of the indolent non-Hodgkin's lymphomas. It is defined as a lymphoma of follicle center B-cells (centrocytes and centroblasts), which has at least a partially follicular pattern.





The tumor is composed of follicle center cells, usually a mixture of centrocytes (cleaved follicle center cells, "small cells") and centroblasts (large noncleaved follicle center cells, "large cells"). Centrocytes typically predominate; centroblasts are usually in the minority, but by definition are always present. Rare lymphomas with a follicular growth pattern consist almost entirely of centroblasts. Occasional cases may show plasmacytoid differentiation or foci of marginal zone or monocytoid B-cells.





There is no consensus regarding the best treatment algorithm, but watch-and-wait policies, alkylators, anthracycline-containing regimens (eg. CHOP), rituximab, autologous and allogeneic stem cell transplanation have all been applied. The disease is regarded as incurable (although allogeneic stem cell transplanation my be curative, the mortality from the procedure is too high to be a first line option). The exception is localised disease, which can be cured by local irradiation. The typical pattern is one of good responses from treatment, followed by relapses some years later. Median survival is around 10 years, but the range is wide, from less than one year, to more than 20 years. Some patients may never need treatment-.

Follicular lymphoma stage 1 treatment?
Surgical removal might be adequate, if there is no other involvement. Prophylactic irradiation may be chosen.
Reply:Talk to your oncologist for your treatment options. Here's more info:


http://www.lymphomainfo.net/nhl/follicul...
Reply:Check this site for the best info:


http://www.leukemia-lymphoma.org/hm_lls


Best wishes
Reply:If it really is stage I (after a full work up including bone marrow biopsy and PET/CT scan), local irradiation may be done with curative intent. On the other hand, depending on the age of the patient and if there is any doubt that it is really stage I, many clinicians would just follow the patient (if they are older), as it is not likely to cause problems for some time.





With any cancer diagnosis, it is important to get a second opinion (with a reall MD, not just on line with Y!A).

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