I want to know the pathology of SCCA and the lymphoma, if a pathologist can be mistaken by the two?
What's the difference between a SCCA from a lymphoma in pathology process?
Assuming SCCA is squamous cell carcinoma, then it is usually quite different from lymphoma.
However, there are poorly differentiated squamous cell carcinoma cases that may not look like typical squamous cells. In such a case, special study such as immunohistochemistry can be performed to confirm epithelial origin and not lymphoid origin.
Typically cytokeratin and CD45 or leukocyte common antigen are used for this purpose. The Pathologist or Pathology lab can be requested to do this test.
The prognosis can be quite different, so it may be worthwhile to pursue this. Nobody is perfect and sometimes on rare occasion tumor cells can be very confusing.
Reply:I doubt it. Lymphatic cells are quite different from squamous cells on slide
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